Successful treatment of surgically induced necrotizing scleritis with tacrolimus

A 46‐year‐old man developed surgically induced necrotizing scleritis (SINS) 7 months following uneventful primary bare sclera pterygium excision. The patient underwent two scleral patch grafts for SINS but despite the use of cyclophos­phamide and azathioprine, the scleral patch grafts failed within...

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Veröffentlicht in:Clinical & experimental ophthalmology 2005-02, Vol.33 (1), p.98-99
Hauptverfasser: Young, Alvin L, Wong, SM, Leung, Alfred TS, Leung, Gloria YS, Cheng, Lulu L, Lam, Dennis SC
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Sprache:eng
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Zusammenfassung:A 46‐year‐old man developed surgically induced necrotizing scleritis (SINS) 7 months following uneventful primary bare sclera pterygium excision. The patient underwent two scleral patch grafts for SINS but despite the use of cyclophos­phamide and azathioprine, the scleral patch grafts failed within 1 month of surgery on both occasions. Tacrolimus was used for his third scleral patch graft. No recurrence of necrotizing scleritis was observed for 2 years. Tacrolimus may be considered as a valuable adjunctive immuno­suppressant in the management of resistant necrotizing scleritis.
ISSN:1442-6404
1442-9071
DOI:10.1111/j.1442-9071.2005.00955.x