Severe leukopenia associated with mild hepatotoxicity in an HIV carrier treated with nevirapine

Nevirapine is a non-nucleoside reverse transcriptase inhibitor used in the treatment of human immunodeficiency virus (HIV)-infected patients and in post-exposure prophylaxis. However, its use has recently been limited because of adverse cutaneous and hepatic effects. We report an HIV-infected woman...

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Veröffentlicht in:Japanese journal of infectious diseases 2004-10, Vol.57 (5), p.212
Hauptverfasser: Shahar, Eduardo, Krivoy, Norberto, Weltfriend, Sara, Pollack, Shimon
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Sprache:eng
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Zusammenfassung:Nevirapine is a non-nucleoside reverse transcriptase inhibitor used in the treatment of human immunodeficiency virus (HIV)-infected patients and in post-exposure prophylaxis. However, its use has recently been limited because of adverse cutaneous and hepatic effects. We report an HIV-infected woman who developed mild leukopenia as the first sign of a nevirapine-related adverse event, which was followed by skin and hepatic toxicity associated with a more severe leukopenia.
ISSN:1344-6304