Synthesis and Molluscicidal Activity of 5-oxo-5,6,7,8-Tetrahydro-4H-Chromene Derivatives

Furfurylidenemalononitriles and thienylidenemalononitriles were treated with 1,3‐cyclohexanediones to afford 2‐amino‐4‐hetaryl‐5‐oxo‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitrile derivatives. The molluscicidal activity of these compounds was investigated.

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Veröffentlicht in:	Archiv der Pharmazie (Weinheim) 2004-09, Vol.337 (9), p.482-485
Hauptverfasser:	Abdelrazek, Fathy M., Metz, Peter, Farrag, Ebtehal K.
Format:	Artikel
Sprache:	eng
Schlagworte:	1,3‐cyclo‐ hexanediones 2-Amino-4-hetaryl-5-oxo-5 2‐Amino‐4‐hetaryl‐5‐oxo‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitriles 3-cyclo- hexanediones 8-tetrahydro-4H-chromene-3-carbonitriles Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Antiparasitic agents Benzopyrans - chemical synthesis Benzopyrans - chemistry Benzopyrans - pharmacology Biological and medical sciences Biomphalaria - drug effects Furfurylidenemalononitriles Medical sciences Molecular Structure Molluscacides - chemical synthesis Molluscacides - chemistry Molluscacides - pharmacology Pharmacology. Drug treatments Structure-Activity Relationship Thienylidenemalononitriles
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Beschreibung
Zusammenfassung:	Furfurylidenemalononitriles and thienylidenemalononitriles were treated with 1,3‐cyclohexanediones to afford 2‐amino‐4‐hetaryl‐5‐oxo‐5,6,7,8‐tetrahydro‐4H‐chromene‐3‐carbonitrile derivatives. The molluscicidal activity of these compounds was investigated.
ISSN:	0365-6233 1521-4184
DOI:	10.1002/ardp.200400881