Loss of consciousness in a child due to loperamide

Loperamide is an antidiarrheal peripheral opiate agonist, with rare neurological secondary effects. We report the case of a 26-month-old child who had impaired consciousness under treatment by loperamide, and was treated successfully with naloxone. Limitations of the use of loperamide in young child...

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Veröffentlicht in:	Archives de pédiatrie : organe officiel de la Société française de pédiatrie 2004-07, Vol.11 (7), p.826
Hauptverfasser:	Chanzy, S, Moretti, S, Mayet, H, Routon, M C, De Gennes, C, Msélati, J C
Format:	Artikel
Sprache:	fre
Schlagworte:	Antidiarrheals - adverse effects Antidiarrheals - therapeutic use Child, Preschool Female Humans Loperamide - adverse effects Loperamide - therapeutic use Naloxone - therapeutic use Narcotic Antagonists - therapeutic use Unconsciousness - chemically induced Unconsciousness - drug therapy
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Zusammenfassung:	Loperamide is an antidiarrheal peripheral opiate agonist, with rare neurological secondary effects. We report the case of a 26-month-old child who had impaired consciousness under treatment by loperamide, and was treated successfully with naloxone. Limitations of the use of loperamide in young children are underlined. Naloxone may be used in case of impaired consciousness, for a diagnostic as well as therapeutic purpose.
ISSN:	0929-693X
DOI:	10.1016/j.arcped.2004.03.123