The effect of mannose binding lectin gene polymorphisms on susceptibility to tuberculosis in different ethnic groups

In order to investigate the role of MBL gene polymorphisms in susceptibility to tuberculosis (TB) we genotyped 487 TB cases and 232 controls. Among African-American individuals, the frequency of B allele was lower among controls than cases (p

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Bibliographische Detailangaben
Veröffentlicht in:	Scandinavian journal of infectious diseases 2004-02, Vol.36 (2), p.106-108
Hauptverfasser:	El Sahly, Hana M., Reich, Robert A., Dou, Shu Jun, Musser, James M., Graviss, Edward A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult African Americans - genetics Aged Bacterial diseases Biological and medical sciences Case-Control Studies Disease Susceptibility DNA, Bacterial - analysis European Continental Ancestry Group - genetics Female Genetic Predisposition to Disease Hispanic Americans - genetics Human bacterial diseases Humans Incidence Infectious diseases Male Mannose-Binding Lectin - genetics Medical sciences Middle Aged Polymerase Chain Reaction Polymorphism, Genetic Probability Reference Values Risk Assessment Sampling Studies Sensitivity and Specificity Tuberculosis and atypical mycobacterial infections Tuberculosis, Pulmonary - ethnology Tuberculosis, Pulmonary - genetics United States - epidemiology
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Beschreibung
Zusammenfassung:	In order to investigate the role of MBL gene polymorphisms in susceptibility to tuberculosis (TB) we genotyped 487 TB cases and 232 controls. Among African-American individuals, the frequency of B allele was lower among controls than cases (p
ISSN:	0036-5548 1651-1980
DOI:	10.1080/00365540310018860