Qualitative and quantitative analysis of three amino acid derivatives of anticonvulsant activity

Qualitative and quantitative methods of analysis of three new amino-acid derivatives potential anticonvulsants of low neurotoxicity: picolinic acid benzylamide (1), nicotinic acid benzylamide (2) and isonicotinic acid benzylamide (3) were developed. Qualitative analysis includes characteristic react...

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Veröffentlicht in:Acta Poloniae pharmaceutica 2003-09, Vol.60 (5), p.335
Hauptverfasser: Pirianowicz-Chaber, Elzbieta, Goldnik, Anna, Paruszewski, Ryszard
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creator Pirianowicz-Chaber, Elzbieta
Goldnik, Anna
Paruszewski, Ryszard
description Qualitative and quantitative methods of analysis of three new amino-acid derivatives potential anticonvulsants of low neurotoxicity: picolinic acid benzylamide (1), nicotinic acid benzylamide (2) and isonicotinic acid benzylamide (3) were developed. Qualitative analysis includes characteristic reactions, chromatographic (TLC) investigations, IR and UV spectra interpretation. The quantitative analysis involves spectophotometric, chromatographic (HPLC) and acidimetric methods.
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subjects Anticonvulsants - analysis
Anticonvulsants - chemistry
Benzyl Compounds - analysis
Benzyl Compounds - chemistry
Chromatography, High Pressure Liquid - methods
Niacin - analogs & derivatives
Niacin - analysis
Niacin - chemistry
Picolinic Acids - analysis
Picolinic Acids - chemistry
Sensitivity and Specificity
Spectrophotometry - methods
title Qualitative and quantitative analysis of three amino acid derivatives of anticonvulsant activity
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