Exploratory and confirmatory gene expression profiling of mac1Delta

Exploratory outlier identification methods and confirmatory gene expression studies showed induction of the iron regulon in Saccharomyces cerevisiae lacking Mac1p, a copper-responsive transcription factor. The Aft1p/Aft2p binding motif was the most discriminating motif between up- and down-regulated...

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Veröffentlicht in:	The Journal of biological chemistry 2004-02, Vol.279 (6), p.4450
Hauptverfasser:	De Freitas, Jeane Maria, Kim, Jeung Hyoun, Poynton, Helen, Su, Trent, Wintz, Henri, Fox, Tama, Holman, Patty, Loguinov, Alex, Keles, Sunduz, van der Laan, Mark, Vulpe, Chris
Format:	Artikel
Sprache:	eng
Schlagworte:	Base Sequence Copper - metabolism DNA, Fungal - genetics Gene Deletion Gene Expression Profiling Genes, Fungal Iron - metabolism Models, Biological Mutation Nuclear Proteins - genetics Nuclear Proteins - metabolism Oligonucleotide Array Sequence Analysis Phenotype Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - metabolism Transcription Factors - genetics Transcription Factors - metabolism
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