Significance of gamma-glutamyl transferase (GGT) activity measurements in alcohol-induced hepatic injury
Experimental evidence is presented that the determination of gamma-glutamyl transferase (GGT) activity in serum is useful in the assessment of alcohol-induced liver disease and for demonstrating to patients the toxic effects of their drinking habits on the liver. Serial measurements of GGT activity...
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| Veröffentlicht in: | Annals of clinical and laboratory science 1977-01, Vol.7 (1), p.25 |
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| container_title | Annals of clinical and laboratory science |
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| creator | Boone, D J Tietz, N W Weinstock, A |
| description | Experimental evidence is presented that the determination of gamma-glutamyl transferase (GGT) activity in serum is useful in the assessment of alcohol-induced liver disease and for demonstrating to patients the toxic effects of their drinking habits on the liver. Serial measurements of GGT activity in serum have also proved valuable in monitoring the progress of therapy as well as alleged abstention from alcohol in the known alcoholic. |
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Serial measurements of GGT activity in serum have also proved valuable in monitoring the progress of therapy as well as alleged abstention from alcohol in the known alcoholic.</description><identifier>ISSN: 0091-7370</identifier><identifier>PMID: 13703</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Alanine Transaminase - blood ; Alcoholism - enzymology ; Alkaline Phosphatase - blood ; Aspartate Aminotransferases - blood ; Chemical and Drug Induced Liver Injury ; Female ; gamma-Glutamyltransferase - blood ; gamma-Glutamyltransferase - metabolism ; Humans ; L-Lactate Dehydrogenase - blood ; Liver Diseases - enzymology ; Male ; Middle Aged ; Time Factors</subject><ispartof>Annals of clinical and laboratory science, 1977-01, Vol.7 (1), p.25</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/13703$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Boone, D J</creatorcontrib><creatorcontrib>Tietz, N W</creatorcontrib><creatorcontrib>Weinstock, A</creatorcontrib><title>Significance of gamma-glutamyl transferase (GGT) activity measurements in alcohol-induced hepatic injury</title><title>Annals of clinical and laboratory science</title><addtitle>Ann Clin Lab Sci</addtitle><description>Experimental evidence is presented that the determination of gamma-glutamyl transferase (GGT) activity in serum is useful in the assessment of alcohol-induced liver disease and for demonstrating to patients the toxic effects of their drinking habits on the liver. Serial measurements of GGT activity in serum have also proved valuable in monitoring the progress of therapy as well as alleged abstention from alcohol in the known alcoholic.</description><subject>Adult</subject><subject>Alanine Transaminase - blood</subject><subject>Alcoholism - enzymology</subject><subject>Alkaline Phosphatase - blood</subject><subject>Aspartate Aminotransferases - blood</subject><subject>Chemical and Drug Induced Liver Injury</subject><subject>Female</subject><subject>gamma-Glutamyltransferase - blood</subject><subject>gamma-Glutamyltransferase - metabolism</subject><subject>Humans</subject><subject>L-Lactate Dehydrogenase - blood</subject><subject>Liver Diseases - enzymology</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Time Factors</subject><issn>0091-7370</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1977</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNotj81KxDAURrNw0HH0CdxkqYtA2tu0zVIGrcKAC8f1cJufNkOTKU0q9O0t6uqDc-DAd0W2nMuMVVDxG3Ib45nzXBYFvyabbGWwJf2n64KzTmFQhl4s7dB7ZN0wJ_TLQNOEIVozYTT0sWmOTxRVct8uLdQbjPNkvAkpUhcoDurSXwbmgp6V0bQ3IyanVnWep-WObCwO0dz_7458vb4c92_s8NG8758PbMx5kVgJtpQZVyCqtQEgbKl1XWkLSslS51aYohWCyyqHTCpRmrySAmoA21rEGnbk4a87zq03-jROzuO0nH7_wg_UolH5</recordid><startdate>197701</startdate><enddate>197701</enddate><creator>Boone, D J</creator><creator>Tietz, N W</creator><creator>Weinstock, A</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>197701</creationdate><title>Significance of gamma-glutamyl transferase (GGT) activity measurements in alcohol-induced hepatic injury</title><author>Boone, D J ; Tietz, N W ; Weinstock, A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p204t-63f6910c357ced335f6dd87df3cc96d2f5e4b550972319c56e27953833fbfaa83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1977</creationdate><topic>Adult</topic><topic>Alanine Transaminase - blood</topic><topic>Alcoholism - enzymology</topic><topic>Alkaline Phosphatase - blood</topic><topic>Aspartate Aminotransferases - blood</topic><topic>Chemical and Drug Induced Liver Injury</topic><topic>Female</topic><topic>gamma-Glutamyltransferase - blood</topic><topic>gamma-Glutamyltransferase - metabolism</topic><topic>Humans</topic><topic>L-Lactate Dehydrogenase - blood</topic><topic>Liver Diseases - enzymology</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Time Factors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Boone, D J</creatorcontrib><creatorcontrib>Tietz, N W</creatorcontrib><creatorcontrib>Weinstock, A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Annals of clinical and laboratory science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Boone, D J</au><au>Tietz, N W</au><au>Weinstock, A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Significance of gamma-glutamyl transferase (GGT) activity measurements in alcohol-induced hepatic injury</atitle><jtitle>Annals of clinical and laboratory science</jtitle><addtitle>Ann Clin Lab Sci</addtitle><date>1977-01</date><risdate>1977</risdate><volume>7</volume><issue>1</issue><spage>25</spage><pages>25-</pages><issn>0091-7370</issn><abstract>Experimental evidence is presented that the determination of gamma-glutamyl transferase (GGT) activity in serum is useful in the assessment of alcohol-induced liver disease and for demonstrating to patients the toxic effects of their drinking habits on the liver. Serial measurements of GGT activity in serum have also proved valuable in monitoring the progress of therapy as well as alleged abstention from alcohol in the known alcoholic.</abstract><cop>United States</cop><pmid>13703</pmid></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0091-7370 |
| ispartof | Annals of clinical and laboratory science, 1977-01, Vol.7 (1), p.25 |
| issn | 0091-7370 |
| language | eng |
| recordid | cdi_pubmed_primary_13703 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adult Alanine Transaminase - blood Alcoholism - enzymology Alkaline Phosphatase - blood Aspartate Aminotransferases - blood Chemical and Drug Induced Liver Injury Female gamma-Glutamyltransferase - blood gamma-Glutamyltransferase - metabolism Humans L-Lactate Dehydrogenase - blood Liver Diseases - enzymology Male Middle Aged Time Factors |
| title | Significance of gamma-glutamyl transferase (GGT) activity measurements in alcohol-induced hepatic injury |
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