Significance of gamma-glutamyl transferase (GGT) activity measurements in alcohol-induced hepatic injury

Experimental evidence is presented that the determination of gamma-glutamyl transferase (GGT) activity in serum is useful in the assessment of alcohol-induced liver disease and for demonstrating to patients the toxic effects of their drinking habits on the liver. Serial measurements of GGT activity...

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Veröffentlicht in:	Annals of clinical and laboratory science 1977-01, Vol.7 (1), p.25
Hauptverfasser:	Boone, D J, Tietz, N W, Weinstock, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Alanine Transaminase - blood Alcoholism - enzymology Alkaline Phosphatase - blood Aspartate Aminotransferases - blood Chemical and Drug Induced Liver Injury Female gamma-Glutamyltransferase - blood gamma-Glutamyltransferase - metabolism Humans L-Lactate Dehydrogenase - blood Liver Diseases - enzymology Male Middle Aged Time Factors
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Beschreibung
Zusammenfassung:	Experimental evidence is presented that the determination of gamma-glutamyl transferase (GGT) activity in serum is useful in the assessment of alcohol-induced liver disease and for demonstrating to patients the toxic effects of their drinking habits on the liver. Serial measurements of GGT activity in serum have also proved valuable in monitoring the progress of therapy as well as alleged abstention from alcohol in the known alcoholic.
ISSN:	0091-7370