Overall analysis of structural factors responsible for the activity and toxicity of antiparasitic agents used in therapy

Overall analysis of structural factors responsible for the activity and toxicity of antiparasitic agents used in therapy

A mini-data bank was constituted from the 73 french antiparasitic patent medicines and was implanted in microcomputer. A maximum of chemical, pharmaceutical, therapeutical and toxicological data were collected and treated by multivariate analysis. Exploitation of these informations processing allows...

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Veröffentlicht in:Bulletin de la Societe de pathologie exotique (1990) 1992, Vol.85 (2), p.180
Hauptverfasser: Lacroix, J, Dore, J C, Viel, C, Lacroix, R, Beliveau, F, Reynouard, F
Format: Artikel
Sprache:fre
Schlagworte:
Anthelmintics - adverse effects
Anthelmintics - pharmacology
Antiprotozoal Agents - adverse effects
Antiprotozoal Agents - pharmacology
Humans
Structure-Activity Relationship
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Beschreibung
Zusammenfassung:A mini-data bank was constituted from the 73 french antiparasitic patent medicines and was implanted in microcomputer. A maximum of chemical, pharmaceutical, therapeutical and toxicological data were collected and treated by multivariate analysis. Exploitation of these informations processing allows to take out correlations between chemical structure toxicity, and specificity.
ISSN:0037-9085