Specificity of Antineoplastic Phenomenon Induced in Mice by Carcinogenic Agents

Summary When mice were inoculated with 3 carcinogenic compounds, they developed a transient antineoplastic (AN) response which was demonstrable by tissue culture technic. This AN phenomenon appeared to be chemically and genetically specific. The duration of the AN response to the 3 agents may repres...

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Veröffentlicht in:	Experimental biology and medicine (Maywood, N.J.) N.J.), 1954-05, Vol.86 (1), p.186-190
Hauptverfasser:	Pollard, Morris, Bussell, Robert H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic Agents Carcinogens - pharmacology Mice Neoplasms, Experimental Sensitivity and Specificity
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Summary When mice were inoculated with 3 carcinogenic compounds, they developed a transient antineoplastic (AN) response which was demonstrable by tissue culture technic. This AN phenomenon appeared to be chemically and genetically specific. The duration of the AN response to the 3 agents may represent the latent period of carcinogenesis, since the AN phenomenon disappeared when the tumor emerged. The interpretation of the AN phenomenon on an immunological basis is discussed.
ISSN:	0037-9727 1535-3702 1535-3699
DOI:	10.3181/00379727-86-21045