Cocaine related fulminant liver failure

A 23-year-old woman developed biochemical signs of acute severe hepatitis together with confusion and flapping tremor after snorting a large dose of cocaine. Blood levels of cocaine were very high and liver biopsy performed few days later showed centrilobular necrosis. She recovered completely with...

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Veröffentlicht in:	Anales de medicina interna (Madrid, Spain : 1984) Spain : 1984), 2002-07, Vol.19 (7), p.365
Hauptverfasser:	Campos Franco, J, Martínez Rey, C, Pérez Becerra, E, González Quintela, A
Format:	Artikel
Sprache:	spa
Schlagworte:	Adult Chemical and Drug Induced Liver Injury - etiology Chemical and Drug Induced Liver Injury - pathology Cocaine - poisoning Cocaine-Related Disorders - complications Female Humans Liver Failure, Acute - chemically induced Liver Failure, Acute - pathology Necrosis
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Zusammenfassung:	A 23-year-old woman developed biochemical signs of acute severe hepatitis together with confusion and flapping tremor after snorting a large dose of cocaine. Blood levels of cocaine were very high and liver biopsy performed few days later showed centrilobular necrosis. She recovered completely with conservative measures. Cocaine toxicity should be considered in similar cases of fulminant liver failure.
ISSN:	0212-7199