Quantitative analysis of pharmaceuticals in biological fluids using high-performance liquid chromatography coupled to mass spectrometry: a review

1. The development of bio-analysis of drug molecules over the last 10 years is reviewed, focusing on advances in sample preparation, liquid chromatography and detection. 2. Developments have led to improvements in detection sensitivity, enhancements in specificity and increased capacity. 3. Emerging...

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Veröffentlicht in:	Xenobiotica 2001, Vol.31 (8-9), p.599-617
Hauptverfasser:	Plumb, R. S., Dear, G. J., Mallett, D. N., Higton, D. M., Pleasance, S., Biddlecombe, R. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Fluids - chemistry Chromatography, High Pressure Liquid - instrumentation Chromatography, High Pressure Liquid - methods Humans Mass Spectrometry - instrumentation Mass Spectrometry - methods Pharmaceutical Preparations - analysis Robotics
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