Structures of azaspiracid analogs, azaspiracid-4 and azaspiracid-5, causative toxins of azaspiracid poisoning in Europe

Two new analogs of azaspiracid, azaspiracid-4 and azaspiracid-5, isolated from the mussel Mytilus edulis, involved in a newly emerged shellfish poisoning in Europe were determined to be 3-hydroxy-22-demethylazaspiracid and 23-hydroxy-22-demethylazaspiracid, respectively.

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Bibliographische Detailangaben
Veröffentlicht in:	Bioscience, biotechnology, and biochemistry biotechnology, and biochemistry, 2001-03, Vol.65 (3), p.740-742
Hauptverfasser:	Ofuji, K. (Tohoku Univ., Sendai (Japan)), Satake, M, Mcmahon, T, James, K.J, Naoki, H, Oshima, Y, Yasumoto, T
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal poisons toxicology. Antivenoms Animals azaspiracid azaspiracid analogs Biological and medical sciences Bivalvia - chemistry CHEMICAL STRUCTURE EUROPE Foodborne Diseases Heterocyclic Compounds, 3-Ring - chemistry Humans Marine Toxins - chemistry Marine Toxins - isolation & purification Medical sciences Molecular Structure MYTILUS EDULIS POISONING shellfish poisoning Spiro Compounds - chemistry Spiro Compounds - isolation & purification Toxicology TOXINS
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Beschreibung
Zusammenfassung:	Two new analogs of azaspiracid, azaspiracid-4 and azaspiracid-5, isolated from the mussel Mytilus edulis, involved in a newly emerged shellfish poisoning in Europe were determined to be 3-hydroxy-22-demethylazaspiracid and 23-hydroxy-22-demethylazaspiracid, respectively.
ISSN:	0916-8451 1347-6947
DOI:	10.1271/bbb.65.740