Efficacy of Octreotide and Sclerotherapy in the Treatment of Acute Variceal Bleeding in Cirrhotic Patients: A Prospective, Multicentric, and Randomized Clinical Trial

Background: Sclerotherapy is the most widely used method for treatment of acute variceal bleeding. Previous reports have suggested that octreotide infusion is as effective as sclerotherapy. Our aim was to investigate the efficacy and safety of octreotide in comparison with sclerotherapy in controlli...

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Veröffentlicht in:	Scandinavian journal of gastroenterology 2000, Vol.35 (4), p.419-425
1. Verfasser:	Bildozola, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adult Aged Biological and medical sciences Chi-Square Distribution Digestive system Esophageal and Gastric Varices - drug therapy Esophageal and Gastric Varices - therapy Female Gastrointestinal Agents - therapeutic use Gastrointestinal Hemorrhage - drug therapy Gastrointestinal Hemorrhage - therapy Humans Liver Cirrhosis - complications Logistic Models Male Medical sciences Middle Aged Octreotide - therapeutic use Pharmacology. Drug treatments Prospective Studies Recurrence Sclerotherapy Treatment Outcome Tropical medicine
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Zusammenfassung:	Background: Sclerotherapy is the most widely used method for treatment of acute variceal bleeding. Previous reports have suggested that octreotide infusion is as effective as sclerotherapy. Our aim was to investigate the efficacy and safety of octreotide in comparison with sclerotherapy in controlling variceal bleeding. Methods: Seventy-six cirrhotic patients were randomized to receive either sclerotherapy (n = 37) or octreotide (n
ISSN:	0036-5521 1502-7708
DOI:	10.1080/003655200750024001