Oral-absorption-enhancing drug-delivery technology
Use of intestinal-absorption enhancers to improve the oral delivery of poorly permeable drug compounds is an important consideration in solid-dosage formulation development. The authors examine an oral-absorption-enhancement technology based on surface-active materials to increase apical membrane fl...
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| Veröffentlicht in: | Pharmaceutical Technology 2011-04, Vol.35 (4), p.S12 |
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| creator | Walsh, Edwin G Cullen, Alan P Fox, John S Leonard, Thomas W |
| description | Use of intestinal-absorption enhancers to improve the oral delivery of poorly permeable drug compounds is an important consideration in solid-dosage formulation development. The authors examine an oral-absorption-enhancement technology based on surface-active materials to increase apical membrane fluidity in vitro and to increase in vivo the transcellular transport of normally excluded molecules. [PUBLICATION ABSTRACT] |
| format | Magazinearticle |
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| fulltext | fulltext |
| identifier | ISSN: 1543-2521 |
| ispartof | Pharmaceutical Technology, 2011-04, Vol.35 (4), p.S12 |
| issn | 1543-2521 2150-7376 |
| language | eng |
| recordid | cdi_proquest_reports_865046852 |
| source | EBSCOhost Business Source Complete; Alma/SFX Local Collection |
| subjects | Absorption (Physiology) Amino acids Bioavailability Drug delivery systems Drug dosages Drug formularies Drugs Gastrointestinal surgery Glycoproteins Metabolism Permeability Pharmaceutical industry R&D Research & development Small intestine Surfactants Vehicles |
| title | Oral-absorption-enhancing drug-delivery technology |
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