Ocular manifestations of mycoplasma-induced rash, mucositis

DIAGNOSIS AND TREATMENT The initial infectious workup was negative, which included blood culture, Group A Streptococcus rapid antigen screen, and nasopharyngeal swab polymerase chain reaction (PCR) testing for adenovirus, coronavirus, human metapneumovirus, rhinovirus, influenza A, influenza B, parainfluenza, respiratory syncytial virus, Bordetella pertussis, Chlamydophila pneumoniae, and Mycoplasma pneumoniae. Of the reported cases of MIRM in the literature, the mean age of presentation was 21.4 years (range 8-46), and all had conjunctival involvement without corneal involvement except for the 1 patient reported by Santos et al.5-10 Santos et al treated the patient with ocular occlusion, topic oxytetracycline ointment, and intravenous immunoglobulins at a dosage of 1 g/kg/d for 3 days with rapid improvement.8 None of the reported cases required amniotic membrane transplant and all recovered without ocular sequelae except for 1 with eyelid margin scar affecting the meibomian glands.9 CONCLUSION There have been no established treatment guidelines for ocular involvement of MIRM. Pediatricians and ophthalmologists should be familiar with this disease entity and consider amniotic membrane transplantation as an additional treatment option when the patient's clinical course worsens while on topical therapy. * In severe cases, amniotic membrane transplantation can afford patients symptomatic pain relief and aid in visual recovery.