Affinity Chromatography from Textile Dyes to Synthetic Ligands by Design, Part 2

Curling highlights the properties of synthetic ligands used in affinity chromatography of biopharmaceuticals with emphasis on the safety and the use of triazinyl ligands. Initially, dye ligands were pursued not only for their biomimetic function but also because they were readily available from major chemical companies; they were cheap and they were stable when attached to a support matrix. Details of the discussion of ligands are presented.