Using compact mass spectrometry for detection and quantification of cannabis-related compounds

The transition of cannabis from an illegal drug to a drug for medical and even recreational use raises challenging questions for regulatory agencies and analytical chemists alike. Here, we show a selection of analytical techniques based on compact mass spectrometry (MS) in combination with three different sample inlets (atmospheric solids analysis probe, thin-layer chromatography [TLC], and classical liquid chromatography [LC]) for the detection and quantification of cannabinoids and pesticides in cannabis-related material and contraband.