LIQUID NITROGEN REACTION COOLING

Two common cooling methods can be used to keep temperatures sufficiently low and control an exothermic reaction: lowtemperature mechanical refrigeration and cryogenic refrigeration via sublimation of carbon dioxide or evaporation of liquid nitrogen (LIN). When the temperature requirements drop lower than -58°F (-50°C), the chiller system becomes more complex with a multi-stage cascade design and multiple refrigerants.1 It also is known that mechanical refrigeration provides a limited ability to cope with widely or rapidly varying heat loads.2 Cryogenic refrigeration provides much more flexibility in terms of temperature ranges and cooling regime variability when compared to mechanical refrigeration.