Comparative Study of the Expression of ATF-3 and ATF-4 Genes in Vessels Involved into Atherosclerosis Process and in Psoriatic Skin
Expression of ATF-3 and ATF-4 genes was examined quantitatively by real-time PCR and changes in the expression of these genes in atherosclerotic lesions and in psoriatic skin were demonstrated. It was found that concomitant pathologies do not affect the expression of these genes. Opposite changes in...
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| Veröffentlicht in: | Bulletin of experimental biology and medicine 2011-10, Vol.151 (6), p.713-716 |
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| container_title | Bulletin of experimental biology and medicine |
| container_volume | 151 |
| creator | Sobolev, V. V. Starodubtseva, N. L. Piruzyan, A. L. Minnibaev, M.T. Sautin, M. E. Tumanov, V. P. Bruskin, S. A. |
| description | Expression of
ATF-3
and
ATF-4
genes was examined quantitatively by real-time PCR and changes in the expression of these genes in atherosclerotic lesions and in psoriatic skin were demonstrated. It was found that concomitant pathologies do not affect the expression of these genes. Opposite changes in the expression of
ATF-3
and
ATF-4
genes in atherosclerotic and psoriatic samples were revealed and a hypothesis was put forward that this parameter could be a criterion of pathological process in both diseases. |
| doi_str_mv | 10.1007/s10517-011-1423-8 |
| format | Article |
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ATF-3
and
ATF-4
genes was examined quantitatively by real-time PCR and changes in the expression of these genes in atherosclerotic lesions and in psoriatic skin were demonstrated. It was found that concomitant pathologies do not affect the expression of these genes. Opposite changes in the expression of
ATF-3
and
ATF-4
genes in atherosclerotic and psoriatic samples were revealed and a hypothesis was put forward that this parameter could be a criterion of pathological process in both diseases.</description><identifier>ISSN: 0007-4888</identifier><identifier>EISSN: 1573-8221</identifier><identifier>DOI: 10.1007/s10517-011-1423-8</identifier><identifier>PMID: 22485215</identifier><identifier>CODEN: BEXBAN</identifier><language>eng</language><publisher>Boston: Springer US</publisher><subject>Activating Transcription Factor 3 - genetics ; Activating Transcription Factor 4 - genetics ; Atherosclerosis ; Atherosclerosis - genetics ; Biomedical and Life Sciences ; Biomedicine ; Cell Biology ; Cholesterol ; Genes ; Genetic aspects ; Genetic transcription ; Genetics ; Humans ; In Vitro Techniques ; Indexing in process ; Internal Medicine ; Laboratory Medicine ; Pathology ; Protein binding ; Proteins ; Psoriasis ; Psoriasis - genetics ; Real-Time Polymerase Chain Reaction ; Skin ; Skin - metabolism</subject><ispartof>Bulletin of experimental biology and medicine, 2011-10, Vol.151 (6), p.713-716</ispartof><rights>Springer Science+Business Media, Inc. 2011</rights><rights>COPYRIGHT 2011 Springer</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c501t-6be4ca6da7394c7b5c6c8261e76c73eff2554cb663a71beaa5e29f0e70fbd9903</citedby><cites>FETCH-LOGICAL-c501t-6be4ca6da7394c7b5c6c8261e76c73eff2554cb663a71beaa5e29f0e70fbd9903</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s10517-011-1423-8$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s10517-011-1423-8$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/22485215$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Sobolev, V. V.</creatorcontrib><creatorcontrib>Starodubtseva, N. L.</creatorcontrib><creatorcontrib>Piruzyan, A. L.</creatorcontrib><creatorcontrib>Minnibaev, M.T.</creatorcontrib><creatorcontrib>Sautin, M. E.</creatorcontrib><creatorcontrib>Tumanov, V. P.</creatorcontrib><creatorcontrib>Bruskin, S. A.</creatorcontrib><title>Comparative Study of the Expression of ATF-3 and ATF-4 Genes in Vessels Involved into Atherosclerosis Process and in Psoriatic Skin</title><title>Bulletin of experimental biology and medicine</title><addtitle>Bull Exp Biol Med</addtitle><addtitle>Bull Exp Biol Med</addtitle><description>Expression of
ATF-3
and
ATF-4
genes was examined quantitatively by real-time PCR and changes in the expression of these genes in atherosclerotic lesions and in psoriatic skin were demonstrated. It was found that concomitant pathologies do not affect the expression of these genes. Opposite changes in the expression of
ATF-3
and
ATF-4
genes in atherosclerotic and psoriatic samples were revealed and a hypothesis was put forward that this parameter could be a criterion of pathological process in both diseases.</description><subject>Activating Transcription Factor 3 - genetics</subject><subject>Activating Transcription Factor 4 - genetics</subject><subject>Atherosclerosis</subject><subject>Atherosclerosis - genetics</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cell Biology</subject><subject>Cholesterol</subject><subject>Genes</subject><subject>Genetic aspects</subject><subject>Genetic transcription</subject><subject>Genetics</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Indexing in process</subject><subject>Internal Medicine</subject><subject>Laboratory Medicine</subject><subject>Pathology</subject><subject>Protein binding</subject><subject>Proteins</subject><subject>Psoriasis</subject><subject>Psoriasis - genetics</subject><subject>Real-Time Polymerase Chain Reaction</subject><subject>Skin</subject><subject>Skin - metabolism</subject><issn>0007-4888</issn><issn>1573-8221</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>BENPR</sourceid><recordid>eNp9kttu1DAQhiMEokvhAbhBFkjATYoPsZNcrlZtqVSJSi3cWo4z6bpk7cVOVvSaF2eyKYciQJZ8GH_z22P_Wfac0SNGafkuMSpZmVPGclZwkVcPsgWTJU44Zw-zBUUoL6qqOsiepHQzLalij7MDzotKciYX2bdV2GxNNIPbAbkcxvaWhI4MayDHX7cRUnLBT5Hl1UkuiPHtflaQU_CQiPPkEzLQJ3Lmd6HfQYuxIZAlKsSQbD_1LpGLGCyCewFMukghOjzTksvPzj_NHnWmT_DsbjzMPp4cX63e5-cfTs9Wy_PcSsqGXDVQWKNaU4q6sGUjrbIVVwxKZUsBXcelLGyjlDAla8AYCbzuKJS0a9q6puIwezPrbmP4MkIa9MYlC31vPIQx6boWjOL7SSTf_pdkjEsuC6EqRF_-gd6EMXqsQ9eUVnjuHno1Q9emB-18F4Zo7KSpl0IqIUWpBFJHf6GwtbBxNnjoHMbvJbz-LWENph_WKfTjgJ-W7oNsBi1-R4rQ6W10GxNvNaN6spKeraTRSnqykp7u_OKusLHZQPsz44d3EOAzkHDLX0P8Vfm_Vb8DBtvQnQ</recordid><startdate>20111001</startdate><enddate>20111001</enddate><creator>Sobolev, V. 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V. ; Starodubtseva, N. L. ; Piruzyan, A. L. ; Minnibaev, M.T. ; Sautin, M. E. ; Tumanov, V. P. ; Bruskin, S. A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c501t-6be4ca6da7394c7b5c6c8261e76c73eff2554cb663a71beaa5e29f0e70fbd9903</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Activating Transcription Factor 3 - genetics</topic><topic>Activating Transcription Factor 4 - genetics</topic><topic>Atherosclerosis</topic><topic>Atherosclerosis - genetics</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cell Biology</topic><topic>Cholesterol</topic><topic>Genes</topic><topic>Genetic aspects</topic><topic>Genetic transcription</topic><topic>Genetics</topic><topic>Humans</topic><topic>In Vitro Techniques</topic><topic>Indexing in process</topic><topic>Internal Medicine</topic><topic>Laboratory Medicine</topic><topic>Pathology</topic><topic>Protein binding</topic><topic>Proteins</topic><topic>Psoriasis</topic><topic>Psoriasis - genetics</topic><topic>Real-Time Polymerase Chain Reaction</topic><topic>Skin</topic><topic>Skin - metabolism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sobolev, V. V.</creatorcontrib><creatorcontrib>Starodubtseva, N. L.</creatorcontrib><creatorcontrib>Piruzyan, A. L.</creatorcontrib><creatorcontrib>Minnibaev, M.T.</creatorcontrib><creatorcontrib>Sautin, M. E.</creatorcontrib><creatorcontrib>Tumanov, V. P.</creatorcontrib><creatorcontrib>Bruskin, S. 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V.</au><au>Starodubtseva, N. L.</au><au>Piruzyan, A. L.</au><au>Minnibaev, M.T.</au><au>Sautin, M. E.</au><au>Tumanov, V. P.</au><au>Bruskin, S. A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Comparative Study of the Expression of ATF-3 and ATF-4 Genes in Vessels Involved into Atherosclerosis Process and in Psoriatic Skin</atitle><jtitle>Bulletin of experimental biology and medicine</jtitle><stitle>Bull Exp Biol Med</stitle><addtitle>Bull Exp Biol Med</addtitle><date>2011-10-01</date><risdate>2011</risdate><volume>151</volume><issue>6</issue><spage>713</spage><epage>716</epage><pages>713-716</pages><issn>0007-4888</issn><eissn>1573-8221</eissn><coden>BEXBAN</coden><abstract>Expression of
ATF-3
and
ATF-4
genes was examined quantitatively by real-time PCR and changes in the expression of these genes in atherosclerotic lesions and in psoriatic skin were demonstrated. It was found that concomitant pathologies do not affect the expression of these genes. Opposite changes in the expression of
ATF-3
and
ATF-4
genes in atherosclerotic and psoriatic samples were revealed and a hypothesis was put forward that this parameter could be a criterion of pathological process in both diseases.</abstract><cop>Boston</cop><pub>Springer US</pub><pmid>22485215</pmid><doi>10.1007/s10517-011-1423-8</doi><tpages>4</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-4888 |
| ispartof | Bulletin of experimental biology and medicine, 2011-10, Vol.151 (6), p.713-716 |
| issn | 0007-4888 1573-8221 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals - AutoHoldings |
| subjects | Activating Transcription Factor 3 - genetics Activating Transcription Factor 4 - genetics Atherosclerosis Atherosclerosis - genetics Biomedical and Life Sciences Biomedicine Cell Biology Cholesterol Genes Genetic aspects Genetic transcription Genetics Humans In Vitro Techniques Indexing in process Internal Medicine Laboratory Medicine Pathology Protein binding Proteins Psoriasis Psoriasis - genetics Real-Time Polymerase Chain Reaction Skin Skin - metabolism |
| title | Comparative Study of the Expression of ATF-3 and ATF-4 Genes in Vessels Involved into Atherosclerosis Process and in Psoriatic Skin |
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