Acute kidney injury following HCT: incidence, risk factors and outcome

Acute kidney injury (AKI) is a common complication in haematopoietic cell transplantation (HCT) patients and it adversely affects outcome. Herein, we provide a comprehensive and contemporary discussion of the incidence, risk factors and outcome of AKI in patients undergoing HCT, focusing on the diff...

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Veröffentlicht in:	Bone marrow transplantation (Basingstoke) 2011-11, Vol.46 (11), p.1399-1408
Hauptverfasser:	Lopes, J A, Jorge, S
Format:	Artikel
Sprache:	eng
Schlagworte:	692/699/1585/4 692/700/565/545/576/1955 Acute Kidney Injury - epidemiology Acute Kidney Injury - etiology Acute Kidney Injury - mortality Acute renal failure Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Bone marrow Bone marrow, stem cells transplantation. Graft versus host reaction Cell Biology Cyclosporine - adverse effects Distribution Graft vs Host Disease - complications Hematology Hematopoietic Stem Cell Transplantation - adverse effects Hematopoietic stem cells Hepatic Veno-Occlusive Disease - complications Humans Incidence Internal Medicine Kidneys Medical sciences Medicine Medicine & Public Health Myeloablative Agonists - adverse effects Nephrology. Urinary tract diseases Patient outcomes Public Health review Risk analysis Risk Factors Stem cell transplantation Stem Cells Transfusions. Complications. Transfusion reactions. Cell and gene therapy Transplantation Transplantation Conditioning - adverse effects Treatment Outcome Urinary system involvement in other diseases. Miscellaneous
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Beschreibung
Zusammenfassung:	Acute kidney injury (AKI) is a common complication in haematopoietic cell transplantation (HCT) patients and it adversely affects outcome. Herein, we provide a comprehensive and contemporary discussion of the incidence, risk factors and outcome of AKI in patients undergoing HCT, focusing on the differences between the myeloablative and nonmyeloablative regimens.
ISSN:	0268-3369 1476-5365
DOI:	10.1038/bmt.2011.46