Biomechanical characterisation of a degradable magnesium-based (MgCa0.8) screw

Magnesium alloys have been in the focus of research in recent years as degradable biomaterial. The purpose of this study was the biomechanical characterisation of MgCa0.8-screws. The maximum pull out force of screws was determined in a synthetic bone without corrosion and after fixed intervals of co...

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Veröffentlicht in:Journal of materials science. Materials in medicine 2012-03, Vol.23 (3), p.649-655
Hauptverfasser: Waizy, Hazibullah, Weizbauer, Andreas, Maibaum, Matthias, Witte, Frank, Windhagen, Henning, Lucas, Arne, Denkena, Berend, Meyer-Lindenberg, Andrea, Thorey, Fritz
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Sprache:eng
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Zusammenfassung:Magnesium alloys have been in the focus of research in recent years as degradable biomaterial. The purpose of this study was the biomechanical characterisation of MgCa0.8-screws. The maximum pull out force of screws was determined in a synthetic bone without corrosion and after fixed intervals of corrosion: 24, 48, 72 and 96 h. This in vitro study has been carried out with Hank’s solution with a flow rate corresponding to the blood flow in natural bone. A maximum pull out force (F max ) of 201.5 ± 9.3 N was measured without corrosion. The biomechanical parameter decreased by 30% after 96 h in corrosive medium compared to the non-corrosion group. A maximum load capacity of 28 ± 7.6 N/h was determined. Our biomechanical data suggests that this biodegradable screw provides a promising bone-screw-fixation and has great potential for medical application.
ISSN:0957-4530
1573-4838
DOI:10.1007/s10856-011-4544-8