Global epidemiology of hepatitis B virus infection: New estimates of age-specific HBsAg seroprevalence and endemicity

Highlights ► Systematic review of global hepatitis B prevalence and modeling of data. ► HBsAg-positive persons increased from 223 million in 1990 to 240 million in 2005. ► HBsAg prevalence varied geographically with highest endemicity in sub-Saharan Africa. ► HBsAg prevalence decreased overall but g...

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Veröffentlicht in:	Vaccine 2012-03, Vol.30 (12), p.2212-2219
Hauptverfasser:	Ott, J.J, Stevens, G.A, Groeger, J, Wiersma, S.T
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Age Age distribution Age Factors Aged Aged, 80 and over Allergy and Immunology Antigens Bayesian analysis Cancer Child Child, Preschool Children Chronic infection Cirrhosis Data processing Disease Epidemiology Estimates Fatalities Female Geography Global Health Hepatitis Hepatitis B Hepatitis B surface antigen Hepatitis B surface antigen (HBsAg) Hepatitis B Surface Antigens - blood Hepatitis B virus Hepatitis B, Chronic - epidemiology Humans Immunization Infant Infant, Newborn Infection Infections Literature reviews Liver cancer Low income groups Male Mathematical models Middle Aged Modeling Morbidity Mortality Population Prevalence Reporting requirements Reviews Risk factors Seroepidemiologic Studies Sex Factors Studies Systematic review Vaccines Young Adult
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Beschreibung
Zusammenfassung:	Highlights ► Systematic review of global hepatitis B prevalence and modeling of data. ► HBsAg-positive persons increased from 223 million in 1990 to 240 million in 2005. ► HBsAg prevalence varied geographically with highest endemicity in sub-Saharan Africa. ► HBsAg prevalence decreased overall but global differences exist. ► Demographic changes call for targeted hepatitis B prevention.
ISSN:	0264-410X 1873-2518
DOI:	10.1016/j.vaccine.2011.12.116