Risk stratification of gallbladder polyps (1-2 cm) for surgical intervention with 18F-FDG PET/CT

We assessed the value of (18)F-FDG uptake in the gallbladder polyp (GP) in risk stratification for surgical intervention and the optimal cutoff level of the parameters derived from GP (18)F-FDG uptake for differentiating malignant from benign etiologies in a select, homogeneous group of patients wit...

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Veröffentlicht in:	The Journal of nuclear medicine (1978) 2012-03, Vol.53 (3), p.353-358
Hauptverfasser:	Lee, Jaehoon, Yun, Mijin, Kim, Kyoung-Sik, Lee, Jong-Doo, Kim, Chun K
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - diagnostic imaging Adenocarcinoma - pathology Adenoma - diagnostic imaging Adenoma - pathology Adult Aged Cell Transformation, Neoplastic - pathology False Positive Reactions Female Fluorodeoxyglucose F18 Gallbladder Diseases - diagnostic imaging Gallbladder Diseases - pathology Gallbladder Diseases - surgery Gallbladder Neoplasms - diagnostic imaging Gallbladder Neoplasms - pathology Gallbladder Neoplasms - surgery Gallstones - diagnostic imaging Humans Image Processing, Computer-Assisted Male Middle Aged Polyps - diagnostic imaging Polyps - pathology Polyps - surgery Positron-Emission Tomography - methods Predictive Value of Tests Radiopharmaceuticals Retrospective Studies Risk Assessment ROC Curve Tomography, Emission-Computed - methods
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Zusammenfassung:	We assessed the value of (18)F-FDG uptake in the gallbladder polyp (GP) in risk stratification for surgical intervention and the optimal cutoff level of the parameters derived from GP (18)F-FDG uptake for differentiating malignant from benign etiologies in a select, homogeneous group of patients with 1- to 2-cm GPs. Fifty patients with 1- to 2-cm GPs incidentally found on the CT portion of PET/CT were retrospectively analyzed. All patients had histologic diagnoses. GP (18)F-FDG activity was visually scored positive (≥liver) or negative (
ISSN:	0161-5505 1535-5667
DOI:	10.2967/jnumed.111.093948