Rituximab therapy prevents focal and segmental glomerulosclerosis recurrence after a second renal transplantation

Summary Preventive treatment of focal and segmental glomerusclerosis (FSGS) allograft recurrence in high risk recipients having a prior history of graft loss caused by FSGS recurrence is still a challenging question. We retrospectively identified four patients who underwent a second renal transplant...

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Veröffentlicht in:Transplant international 2012-05, Vol.25 (5), p.e62-e66
Hauptverfasser: Audard, Vincent, Kamar, Nassim, Sahali, Dil, Cardeau‐Desangles, Isabelle, Homs, Sébastien, Remy, Philippe, Aouizerate, Jessie, Matignon, Marie, Rostaing, Lionel, Lang, Philippe, Grimbert, Philippe
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Sprache:eng
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Zusammenfassung:Summary Preventive treatment of focal and segmental glomerusclerosis (FSGS) allograft recurrence in high risk recipients having a prior history of graft loss caused by FSGS recurrence is still a challenging question. We retrospectively identified four patients who underwent a second renal transplantation because of recurrent FSGS and who received Rituximab therapy as a prophylactic treatment. Loss of their first allograft was directly related to an early (
ISSN:0934-0874
1432-2277
DOI:10.1111/j.1432-2277.2012.01462.x