Changing Epidemiology of Abdominal Aortic Aneurysms in England and Wales: Older and More Benign?

Recent studies from Australia, New Zealand, and Sweden have reported declines in abdominal aortic aneurysm (AAA) incidence, prevalence, and mortality. This finding may have important implications for screening programs. This study determined trends in AAA incidence and mortality in England and Wales...

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Veröffentlicht in:Circulation (New York, N.Y.) N.Y.), 2012-04, Vol.125 (13), p.1617-1625
Hauptverfasser: CHOKE, Edward, VIJAYNAGAR, Badri, THOMPSON, John, NASIM, Akhtar, BOWN, Matthew J, SAYERS, Robert D
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Sprache:eng
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Zusammenfassung:Recent studies from Australia, New Zealand, and Sweden have reported declines in abdominal aortic aneurysm (AAA) incidence, prevalence, and mortality. This finding may have important implications for screening programs. This study determined trends in AAA incidence and mortality in England and Wales. Cause-specific mortality data for England and Wales were obtained from UK Office for National Statistics, and hospital admissions and procedures data for England were obtained from Hospital Episode Statistics from 2001 to 2009. Poisson regression models were constructed to estimate the relative change over time. Age-standardized rates for AAA mortality in England and Wales fell significantly by 35.7% from 2001 to 2009, which was largely due to a 35.3% drop in age-standardized ruptured AAA deaths. During the same period, ruptured AAA admissions and emergency AAA repairs in England declined by 29.3% and 35.5%, respectively. In contrast, nonruptured AAA admissions remained static, and nonemergency AAA repairs increased by 17.2%. The average ages for hospital admissions for nonruptured AAAs and ruptured AAAs increased by 0.19 years of age per annum (P
ISSN:0009-7322
1524-4539
DOI:10.1161/CIRCULATIONAHA.111.077503