Controlled self-assembly of [small alpha]-helix-decorated peptide nanostructures

Controlled self-assembly of [small alpha]-helix-decorated peptide nanostructures

This study describes a strategy to control the degree of [small alpha]-helix stabilization and the shape of [small alpha]-helix-decorated nanostructures. Coassembly of a macrocyclic peptide and a [small beta]-sheet peptide diminished steric clashes between helical peptide segments, further stabilizi...

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Veröffentlicht in:Soft matter 2011-01, Vol.7 (5), p.1675-1677
Hauptverfasser: Choi, Sung-ju, Jeong, Woo-jin, Kim, Tae-Hyun, Lim, Yong-beom
Format: Artikel
Sprache:eng
Schlagworte:
Nanocomposites
Nanomaterials
Nanostructure
Peptides
Segments
Self assembly
Stabilization
Strategy
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Beschreibung
Zusammenfassung:This study describes a strategy to control the degree of [small alpha]-helix stabilization and the shape of [small alpha]-helix-decorated nanostructures. Coassembly of a macrocyclic peptide and a [small beta]-sheet peptide diminished steric clashes between helical peptide segments, further stabilizing [small alpha]-helices.
ISSN:1744-683X
DOI:10.1039/C0SM01275K