Fifty-year old samples of progesterone demonstrate the complex role of synthetic impurities in stabilizing a metastable polymorph

Fifty-year old samples of progesterone demonstrate the complex role of synthetic impurities in stabilizing a metastable polymorph

We describe a unique experiment whereby analysis of fifty-year old samples of progesterone shows that a metastable, 'disappearing' polymorph contains several impurities that are not found in the stable form.

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Veröffentlicht in:CrystEngComm 2011-01, Vol.13 (6), p.1775-1777
Hauptverfasser: Lancaster, Robert W, Harris, Lisa D, Pearson, David
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Sprache:eng
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Impurities
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creator Lancaster, Robert W
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description We describe a unique experiment whereby analysis of fifty-year old samples of progesterone shows that a metastable, 'disappearing' polymorph contains several impurities that are not found in the stable form.
doi_str_mv 10.1039/C0CE00858C
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subjects Impurities
title Fifty-year old samples of progesterone demonstrate the complex role of synthetic impurities in stabilizing a metastable polymorph
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