Fabrication of micropatterns of nanoarrays on a polymeric gel surface

Micro-nano patterns of gold on the surface of poly(ethylene glycol) (PEG) hydrogels were prepared. The approach combines the technique of conventional photolithography (a top-down method for micropatterns), block copolymer micelle nanolithography (a bottom-up method for gold nanopatterns), and a lin...

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Veröffentlicht in:Nanoscale 2010-01, Vol.2 (1), p.122-127
Hauptverfasser: Liu, Peng, Sun, Jianguo, Huang, Jinghuan, Peng, Rong, Tang, Jian, Ding, Jiandong
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Sprache:eng
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Zusammenfassung:Micro-nano patterns of gold on the surface of poly(ethylene glycol) (PEG) hydrogels were prepared. The approach combines the technique of conventional photolithography (a top-down method for micropatterns), block copolymer micelle nanolithography (a bottom-up method for gold nanopatterns), and a linker-assistant technique to transfer a pattern on a hard surface to a polymeric surface. Hybrid micro-nano patterns on hydrogels were characterized using scanning electron microscopy, atomic force microscopy and X-ray photoelectron spectroscopy. The patterned Au nanoparticles were further modified by a peptide containing arginine-glycine-aspatate (RGD). The cell-adhesion contrast of the patterned hydrogel surface was confirmed by preliminary cell experiments.
ISSN:2040-3364
2040-3372
DOI:10.1039/b9nr00124g