Different localizations of hydrophobic magnetic nanoparticles within vesicles trigger their efficiency as magnetic nano-heaters

The reverse phase evaporation (REV) and the multiple emulsion (ME) process are used to encapsulate hydrophobic magnetic nanoparticles (MNPs) within vesicles. The effect of the size distribution of the nanoparticles on their location in the liposomes has been observed by transmission electron microscopy: the small ones are in the inner core of the vesicles while the larger ones are found to be located at the membrane level. The influence of the confinement of hydrophobic nanoparticles inside vesicles on their subsequent magnetic properties (relaxometry, heating capacity) has been studied.