Synthesis of injectable and cohesive nano hydroxyapatite scaffolds

Biomimetically synthesized nanosized hydroxyapatite particles have been converted into an injectable paste using a neutral phosphate buffer. Synthesized system manifested a self setting behavior at 37°C in 20 min and revealed a macroporous self assembled microstructure. Stability of the injectable h...

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Veröffentlicht in:	Journal of materials science. Materials in medicine 2012-04, Vol.23 (4), p.913-919
Hauptverfasser:	Varma, Nitin Pratap, Garai, Subhadra, Sinha, Arvind
Format:	Artikel
Sprache:	eng
Schlagworte:	Ball milling Biological and medical sciences Biomaterials Biomedical Engineering and Bioengineering Biomedical materials Biomimetics Blood Ceramics Chemistry and Materials Science Composites Durapatite - chemistry Glass Humans Hydroxyapatite Materials Science Medical sciences Microscopy, Electron, Scanning Microscopy, Electron, Transmission Nanocomposites Nanomaterials Nanoparticles Nanostructure Nanotechnology Natural Materials Pastes Polymer Sciences Regenerative Medicine/Tissue Engineering Stability Surfaces and Interfaces Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology. Biomaterials. Equipments Thin Films X-Ray Diffraction
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Zusammenfassung:	Biomimetically synthesized nanosized hydroxyapatite particles have been converted into an injectable paste using a neutral phosphate buffer. Synthesized system manifested a self setting behavior at 37°C in 20 min and revealed a macroporous self assembled microstructure. Stability of the injectable hydroxyapatite has been confirmed in aqueous medium as well as in human blood. Effect of ball milling was also studied on the stability of the system.
ISSN:	0957-4530 1573-4838
DOI:	10.1007/s10856-012-4579-5