Functional Unity of the Thymus and Pineal Gland and Study of the Mechanisms of Aging

The data on the morphology and functions of the thymus and pineal gland in individuals of different age are analyzed and common mechanisms of involution of these organs during aging and the consequencies of this process are discussed. Based on the data on the molecular changes in the thymus and pine...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2011-09, Vol.151 (5), p.627-630
Hauptverfasser:	Polyakova, V. O., Linkova, N. S., Kvetnoy, I. M., Khavinson, V. Kh
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive Immunity Age Factors Aging Biogerontology Biomedical and Life Sciences Biomedicine Cell Biology Complementarity Data processing Humans Internal Medicine Laboratory Medicine Melatonin - metabolism Pathology Pineal gland Pineal Gland - anatomy & histology Pineal Gland - metabolism Pineal Gland - physiology Serotonin - metabolism Thymus Thymus Gland - anatomy & histology Thymus Gland - metabolism Thymus Gland - physiology
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Beschreibung
Zusammenfassung:	The data on the morphology and functions of the thymus and pineal gland in individuals of different age are analyzed and common mechanisms of involution of these organs during aging and the consequencies of this process are discussed. Based on the data on the molecular changes in the thymus and pineal gland during aging, the authors hypothesize the functional unity of these organs and their mutual complementarity in the maintenance of normal immune and endocrine status during aging.
ISSN:	0007-4888 1573-8221
DOI:	10.1007/s10517-011-1400-2