Endurance training enhances ABCA1 expression in rat small intestine

The purpose of this study was to investigate liver and intestinal ABCA1 expression and plasma HDL-C level in response to treadmill-running training in rats. Twenty adult Wistar male rats (17–18 weeks old, 300–322 g) were divided into control ( n = 10) and Training ( n = 10) groups. Training group...

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Veröffentlicht in:	European journal of applied physiology 2009-10, Vol.107 (3), p.351-358
Hauptverfasser:	Khabazian, Behzad Mehdi, Ghanbari-Niaki, Abbass, Safarzadeh-Golpordesari, Ali reza, Ebrahimi, Mehdi, Rahbarizadeh, Fatemeh, Abednazari, Hossein
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - metabolism Animals Apolipoprotein A-I - metabolism Apolipoproteins Atherosclerosis ATP Binding Cassette Transporter 1 ATP-Binding Cassette Transporters - metabolism Biological and medical sciences Biomedical and Life Sciences Biomedicine Blood Glucose - metabolism Cardiovascular disease Cholesterol Cholesterol, HDL - blood Exercise Fitness equipment Fitness training programs Fundamental and applied biological sciences. Psychology High density lipoprotein Human Physiology Intestine, Small - metabolism Lipoproteins Liver Liver - metabolism Male Musculoskeletal system Occupational Medicine/Industrial Medicine Original Article Physical Conditioning, Animal Physical education Physical Endurance - physiology Physical fitness Plasma Proteins Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction Small intestine Sports Medicine Vertebrates: body movement. Posture. Locomotion. Flight. Swimming. Physical exercise. Rest. Sports
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Zusammenfassung:	The purpose of this study was to investigate liver and intestinal ABCA1 expression and plasma HDL-C level in response to treadmill-running training in rats. Twenty adult Wistar male rats (17–18 weeks old, 300–322 g) were divided into control ( n = 10) and Training ( n = 10) groups. Training group trained at 25 m/min (0% grade) for 60 min/day, 5 days/week for 12 weeks. Rats were killed 48 h after the last session of training. The intestinal and liver ABCA1 mRNA expression was found to be significantly higher in trained compared to control group ( P
ISSN:	1439-6319 1439-6327
DOI:	10.1007/s00421-009-1133-3