Association between nonspecific skeletal pain and vitamin D deficiency

Background: Deficiency of vitamin D has been reported in patients with many types of musculoskeletal pain. The present study was designed to determine the association between serum 25‐hydroxyvitamin D [25‐(OH)D] deficiency and nonspecific skeletal pain. Methods: A total of 276 patients with nonspecific skeletal pain at different regions of the skeletal system diagnosed as leg pain, widespread pain, arthralgia, rib pain, back pain and fibromyalgia were compared with 202 matched controls with regard to mean serum 25‐(OH)D level and 25‐(OH)D deficiency. Serum 25‐(OH)D was measured by enzyme‐linked immunosorbent assay method and levels