Effect of omega-3 fatty acids supplementation on endothelial function: A meta-analysis of randomized controlled trials

Highlights ► We examine the effect of omega-3 FAs on endothelial function by a meta-analysis. ► Flow-mediated dilation was significantly improved by omega-3 FAs supplementation. ► No significant effect on endothelium-independent vasodilation was observed.

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Veröffentlicht in:	Atherosclerosis 2012-04, Vol.221 (2), p.536-543
Hauptverfasser:	Wang, Qianqian, Liang, Xiaohua, Wang, Laiyuan, Lu, Xiangfeng, Huang, Jianfeng, Cao, Jie, Li, Hongfan, Gu, Dongfeng
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiovascular Cardiovascular Diseases - drug therapy Cardiovascular Diseases - physiopathology Cardiovascular system Child confidence interval Dietary Supplements Dose-Response Relationship, Drug Endothelial function Endothelium, Vascular - drug effects Endothelium, Vascular - physiopathology Evidence-Based Medicine Fatty Acids, Omega-3 - administration & dosage Fatty Acids, Omega-3 - therapeutic use Female foot-and-mouth disease health status Humans Male Medical sciences Meta-analysis Middle Aged Omega-3 fatty acids Pharmacology. Drug treatments protective effect randomized clinical trials Randomized Controlled Trials as Topic Regression Analysis risk Time Factors Treatment Outcome vasodilation Vasodilation - drug effects Vasodilator agents. Cerebral vasodilators Young Adult
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Beschreibung
Zusammenfassung:	Highlights ► We examine the effect of omega-3 FAs on endothelial function by a meta-analysis. ► Flow-mediated dilation was significantly improved by omega-3 FAs supplementation. ► No significant effect on endothelium-independent vasodilation was observed.
ISSN:	0021-9150 1879-1484
DOI:	10.1016/j.atherosclerosis.2012.01.006