Circulating endothelial progenitor cells are reduced in SLE in the absence of coronary artery calcification

Circulating endothelial progenitor cells (EPCs) are reduced in patients with systemic lupus erythematosus (SLE). A reduced number of EPCs are associated with the presence of atherosclerosis in other populations. We sought to determine whether the reduction in EPC numbers in SLE is dependent on the p...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Rheumatology international 2012-04, Vol.32 (4), p.997-1002
Hauptverfasser:	Baker, Joshua F., Zhang, Lifeng, Imadojemu, Sotonye, Sharpe, Alexis, Patil, Sarita, Moore, Jonni S., Mohler, Emile R., Von Feldt, Joan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Carotid Intima-Media Thickness Coronary Vessels - pathology Endothelial Cells - pathology Endothelium, Vascular - pathology Female Humans Lupus Erythematosus, Systemic - blood Lupus Erythematosus, Systemic - pathology Male Medicine Medicine & Public Health Middle Aged Original Article Rheumatology Stem Cells - pathology Vascular Calcification - blood Vascular Calcification - pathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Circulating endothelial progenitor cells (EPCs) are reduced in patients with systemic lupus erythematosus (SLE). A reduced number of EPCs are associated with the presence of atherosclerosis in other populations. We sought to determine whether the reduction in EPC numbers in SLE is dependent on the presence of advanced coronary artery calcification (CAC). Patients with SLE had previous coronary calcium scores which placed them in either the >75th percentile or
ISSN:	0172-8172 1437-160X
DOI:	10.1007/s00296-010-1730-9