Case of fatal congenital toxoplasmosis associated with I/III recombinant genotype

We report a case of fatal congenital toxoplasmosis case in Tunis (North of Tunisia) associated with I/III recombinant genotype. The Toxoplasma gondii strain was isolated from placenta and characterized molecularly by a multilocus typing (3'SAG2, 5'SAG2, SAG3, AK69, APICO, and UPRT1) and a...

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Veröffentlicht in:	Tropical Biomedicine 2011-12, Vol.28 (3), p.615-619
Hauptverfasser:	Boughattas, S, Ben-Abdallah, R, Siala, E, Souissi, O, Maatoug, R, Aoun, K, Bouratbine, A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiprotozoal Agents Antiprotozoal Agents - pharmacology DNA, Protozoan DNA, Protozoan - genetics Female Genotype Humans Infant, Newborn Life Sciences Multilocus Sequence Typing Parasitic Sensitivity Tests Placenta Placenta - parasitology Pregnancy Recombination, Genetic Sulfadiazine Sulfadiazine - pharmacology Toxoplasma Toxoplasma - classification Toxoplasma - genetics Toxoplasma - isolation & purification Toxoplasmosis, Congenital Toxoplasmosis, Congenital - diagnosis Toxoplasmosis, Congenital - parasitology Tunisia
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Zusammenfassung:	We report a case of fatal congenital toxoplasmosis case in Tunis (North of Tunisia) associated with I/III recombinant genotype. The Toxoplasma gondii strain was isolated from placenta and characterized molecularly by a multilocus typing (3'SAG2, 5'SAG2, SAG3, AK69, APICO, and UPRT1) and a sulfadiazine resistance mutation analysis. The isolate was shown to be a wild drug sensitive I/III recombinant strain.
ISSN:	0127-5720