New Galloyl Derivative from Winged Sumac (Rhus copallinum) Fruit

Twelve compounds were isolated from Winged Sumac (Rhus copallinum) fruit and their structures were elucidated on the basis of NMR and mass spectral data. The isolates included a new galloyl derivative, (R)-galloyl malic acid dimethyl ester (1), and eleven known compounds, gallic acid (2), methyl gal...

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Veröffentlicht in:	Natural product communications 2012-01, Vol.7 (1), p.45-46
Hauptverfasser:	Ma, Hang, Yuan, Tao, González-Sarrías, Antonio, Li, Liya, Edmonds, Maxwell E., Seeram, Navindra P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents, Phytogenic - isolation & purification Antineoplastic Agents, Phytogenic - pharmacology Cell Line, Tumor Fruit - chemistry Gallic Acid - analogs & derivatives Gallic Acid - isolation & purification Gallic Acid - pharmacology Humans Quercetin - isolation & purification Quercetin - pharmacology Rhus - chemistry
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Zusammenfassung:	Twelve compounds were isolated from Winged Sumac (Rhus copallinum) fruit and their structures were elucidated on the basis of NMR and mass spectral data. The isolates included a new galloyl derivative, (R)-galloyl malic acid dimethyl ester (1), and eleven known compounds, gallic acid (2), methyl gallate (3), glucogallin (4), methyl m-digallate (5), methyl p-digallate (6), quercetin (7), myricetin (8), rhamnazin (9), kaempferol (10), betulinic acid (11), and oleanolic acid (12). All of the compounds were evaluated for antiproliferative effects against human colon tumorigenic (HCT-116, Caco-2) and non-tumorigenic (CCD18-Co) cell lines.
ISSN:	1934-578X 1555-9475
DOI:	10.1177/1934578X1200700116