Viper venom for diabetic nephropathy

Diabetic nephropathy is the leading cause of end-stage renal disease in the United States. Renin–angiotensin–aldosterone system (RAAS) blockers are thought to have a specific renoprotective effect in diabetes. Hirst et al. report the results of randomized clinical trials assessing the effects of RAA...

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Veröffentlicht in:	Kidney international 2012-04, Vol.81 (7), p.615-616, Article 615
1. Verfasser:	Luiza Caramori, M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Diabetes Mellitus, Type 1 - drug therapy Diabetes Mellitus, Type 2 - drug therapy Diabetic Nephropathies - drug therapy Female Humans Male Renin-Angiotensin System - drug effects
Online-Zugang:	Volltext
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Beschreibung
Zusammenfassung:	Diabetic nephropathy is the leading cause of end-stage renal disease in the United States. Renin–angiotensin–aldosterone system (RAAS) blockers are thought to have a specific renoprotective effect in diabetes. Hirst et al. report the results of randomized clinical trials assessing the effects of RAAS inhibitors on urinary albumin excretion levels in diabetic patients. Although reductions in urinary albumin excretion were observed, whether RAAS inhibitors offer additional protection over other antihypertensive agents is unclear.
ISSN:	0085-2538 1523-1755
DOI:	10.1038/ki.2011.460