Recovery of consciousness following acute symptomatic seizures due to central nervous system infections in children

Aim The aim of this study was to assess whether acute symptomatic epileptic seizures associated with central nervous system infections (ASinf) have a different ictal and postictal course to seizures of other aetiologies. Method A case note analysis of 81 children (47 males; 34 females; age range 1mo–15y 6mo; median age 12mo) with central nervous system infections was undertaken. Seizure type, duration, aetiology, and timing were recorded. Recovery time to full consciousness in those not intubated was determined. Intubation rates and recovery times were compared with those from previous studies. Results Of the 81 children, 40 (49.4%) had one or more ASinf. The different aetiologies were bacterial meningitis, aseptic meningitis, abscess/empyema, encephalitis, and postoperative infection. Twenty‐two had status epilepticus. The intubation rate in children with ASinf was higher than that in children with seizures of other aetiologies (21/40 [52.5%] vs 4/124 [3.23%]; p < 0.0001). Median postictal recovery time was 4.33 hours (0–207h). Children with ASinf took 4.3 (p