Reversibly Switching the Function of a Surface between Attacking and Defending against Bacteria
Attack or defend! A smart polymer surface has two reversibly switchable equilibrium states, a cationic N,N‐dimethyl‐2‐morpholinone (CB‐Ring) and a zwitterionic carboxy betaine (CB‐OH). CB‐Ring will kill bacteria upon contact under dry conditions, whereas CB‐OH will release the previously attached an...
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| Veröffentlicht in: | Angewandte Chemie International Edition 2012-03, Vol.51 (11), p.2602-2605 |
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| container_issue | 11 |
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| container_title | Angewandte Chemie International Edition |
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| creator | Cao, Zhiqiang Mi, Luo Mendiola, Jose Ella-Menye, Jean-Rene Zhang, Lei Xue, Hong Jiang, Shaoyi |
| description | Attack or defend! A smart polymer surface has two reversibly switchable equilibrium states, a cationic N,N‐dimethyl‐2‐morpholinone (CB‐Ring) and a zwitterionic carboxy betaine (CB‐OH). CB‐Ring will kill bacteria upon contact under dry conditions, whereas CB‐OH will release the previously attached and dead bacteria and further resist adhesion of bacteria under wet conditions. |
| doi_str_mv | 10.1002/anie.201106466 |
| format | Article |
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A smart polymer surface has two reversibly switchable equilibrium states, a cationic N,N‐dimethyl‐2‐morpholinone (CB‐Ring) and a zwitterionic carboxy betaine (CB‐OH). 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KGaA, Weinheim</rights><rights>Copyright © 2012 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.</rights><rights>Copyright © 2012 WILEY-VCH Verlag GmbH & Co. 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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adhesion Anti-Infective Agents - chemistry Anti-Infective Agents - pharmacology antimicrobial activity Bacteria Bacteria - drug effects Betaine - chemistry Betaines biological activity Cationic Cations - chemistry Contact Drying Escherichia coli - drug effects materials science Morpholines - chemistry Polymers - chemistry Polymers - pharmacology Resists surface chemistry Surface Properties switchable materials Switching |
| title | Reversibly Switching the Function of a Surface between Attacking and Defending against Bacteria |
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