Reversibly Switching the Function of a Surface between Attacking and Defending against Bacteria

Reversibly Switching the Function of a Surface between Attacking and Defending against Bacteria

Attack or defend! A smart polymer surface has two reversibly switchable equilibrium states, a cationic N,N‐dimethyl‐2‐morpholinone (CB‐Ring) and a zwitterionic carboxy betaine (CB‐OH). CB‐Ring will kill bacteria upon contact under dry conditions, whereas CB‐OH will release the previously attached an...

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Veröffentlicht in:Angewandte Chemie International Edition 2012-03, Vol.51 (11), p.2602-2605
Hauptverfasser: Cao, Zhiqiang, Mi, Luo, Mendiola, Jose, Ella-Menye, Jean-Rene, Zhang, Lei, Xue, Hong, Jiang, Shaoyi
Format: Artikel
Sprache:eng
Schlagworte:
Adhesion
Anti-Infective Agents - chemistry
Anti-Infective Agents - pharmacology
antimicrobial activity
Bacteria
Bacteria - drug effects
Betaine - chemistry
Betaines
biological activity
Cationic
Cations - chemistry
Contact
Drying
Escherichia coli - drug effects
materials science
Morpholines - chemistry
Polymers - chemistry
Polymers - pharmacology
Resists
surface chemistry
Surface Properties
switchable materials
Switching
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Beschreibung
Zusammenfassung:Attack or defend! A smart polymer surface has two reversibly switchable equilibrium states, a cationic N,N‐dimethyl‐2‐morpholinone (CB‐Ring) and a zwitterionic carboxy betaine (CB‐OH). CB‐Ring will kill bacteria upon contact under dry conditions, whereas CB‐OH will release the previously attached and dead bacteria and further resist adhesion of bacteria under wet conditions.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.201106466