A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

A mitochondria-localized two-photon fluorescent probe for ratiometric imaging of hydrogen peroxide in live tissue

We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H(2)O(2) in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical communications (Cambridge, England) England), 2012-01, Vol.48 (29), p.3518-3520
Hauptverfasser: Masanta, Goutam, Heo, Cheol Ho, Lim, Chang Su, Bae, Sung Keun, Cho, Bong Rae, Kim, Hwan Myung
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Fluorescent Dyes
Hippocampus
Hydrogen Peroxide - analysis
Microscopy, Fluorescence
Mitochondria
Photons
Rats
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We report a two-photon fluorescent probe (SHP-Mito) which can ratiometrically detect mitochondrial H(2)O(2) in live cells and intact tissues at >100 μm depth through the use of two-photon microscopy.
ISSN:1359-7345
1364-548X
DOI:10.1039/c2cc00034b