Cerebrovascular hemodynamics in Alzheimer's disease and vascular dementia: A meta-analysis of transcranial Doppler studies

Highlights ► Both ageing and dementia are associated with alteration in cerebral hemodynamics. ► We performed a meta-analysis on patterns of cerebral hemodynamics in demented patients compared to healthy elderly subject. ► Patients with Alzheimer's disease and vascular dementia had lower integrity in their arterial perfusion. ► Patients with Alzheimer's disease and vascular dementia had decreased cerebrovascular compliance. ► The magnitude of disturbances in cerebral hemodynamic is greater in vascular dementia compared to Alzheimer's disease.