A fast and easy real-time PCR genotyping method for the HLA-G 14-bp insertion/deletion polymorphism in the 3′ untranslated region

Human leukocyte antigen‐G (HLA‐G) is a non‐classical HLA class Ib molecule shown to exhibit immunomodulatory function in a wide range of immune‐based disorders. A number of functional HLA‐G gene polymorphisms have been identified, including a 14‐bp insertion/deletion polymorphism in exon 8 of the 3′...

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Veröffentlicht in:	Tissue antigens 2012-03, Vol.79 (3), p.186-189
Hauptverfasser:	Djurisic, S., Sørensen, A. E., Hviid, T. V. F.
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated Regions - genetics 3′ untranslated region Alternative splicing Base Sequence Electrophoresis, Polyacrylamide Gel Exons Gene deletion Gene polymorphism Genotyping Genotyping Techniques - methods Histocompatibility antigen HLA HLA-G Antigens - genetics human leukocyte antigen-G Humans Immunomodulation Insertion Leukocytes major histocompatibility complex Molecular Sequence Data mRNA stability Mutagenesis, Insertional Polymerase chain reaction Polymorphism, Genetic polymorphisms Real-Time Polymerase Chain Reaction Reproducibility of Results Sequence Deletion Time Factors
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