Graphene oxide-protected DNA probes for multiplex microRNA analysis in complex biological samples based on a cyclic enzymatic amplification method
Based on graphene oxide-protected DNA probes, we have developed a cyclic enzymatic amplification method for sensitive miRNA detection in complex biological samples. By using the quenching nature of graphene oxide for multiple fluorophores, this method can distinguish highly similar miRNA sequences a...
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| Veröffentlicht in: | Chemical communications (Cambridge, England) England), 2012-01, Vol.48 (2), p.194-196 |
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| container_end_page | 196 |
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| container_issue | 2 |
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| container_title | Chemical communications (Cambridge, England) |
| container_volume | 48 |
| creator | Cui, Liang Lin, Xiaoyan Lin, Ninghang Song, Yanling Zhu, Zhi Chen, Xi Yang, Chaoyong James |
| description | Based on graphene oxide-protected DNA probes, we have developed a cyclic enzymatic amplification method for sensitive miRNA detection in complex biological samples. By using the quenching nature of graphene oxide for multiple fluorophores, this method can distinguish highly similar miRNA sequences and detect them simultaneously. |
| doi_str_mv | 10.1039/c1cc15412e |
| format | Article |
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| ispartof | Chemical communications (Cambridge, England), 2012-01, Vol.48 (2), p.194-196 |
| issn | 1359-7345 1364-548X |
| language | eng |
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| source | MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
| subjects | Biosensing Techniques - methods Chemical communication Deoxyribonuclease I - metabolism DNA Probes - chemistry Fluorescent Dyes - chemistry Graphite - chemistry Humans MicroRNAs - analysis MicroRNAs - metabolism Oxides - chemistry Sensitivity and Specificity |
| title | Graphene oxide-protected DNA probes for multiplex microRNA analysis in complex biological samples based on a cyclic enzymatic amplification method |
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