Microenvironment changes in mild traumatic brain injury

Highlights ► This review discusses microenvironment changes after mild brain injury (MTBI). ► Preclinical and clinical evidence point towards cellular changes after MTBI. ► The microenvironment may explain the decline in behaviour and cognition after MTBI. ► Modulation of the injured microenvironmen...

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Veröffentlicht in:	Brain research bulletin 2012-03, Vol.87 (4), p.359-372
Hauptverfasser:	Kan, Enci Mary, Ling, Eng-Ang, Lu, Jia
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Brain Concussion - complications Brain Concussion - physiopathology Cognition Disorders - etiology Cognition Disorders - physiopathology Humans Microenvironment Mild traumatic brain injury Modulation Neurology Neurometabolism Outcome Pathophysiology
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Beschreibung
Zusammenfassung:	Highlights ► This review discusses microenvironment changes after mild brain injury (MTBI). ► Preclinical and clinical evidence point towards cellular changes after MTBI. ► The microenvironment may explain the decline in behaviour and cognition after MTBI. ► Modulation of the injured microenvironment may improve MTBI prognosis.
ISSN:	0361-9230 1873-2747
DOI:	10.1016/j.brainresbull.2012.01.007