No sweat, a rare case of hidradenocarcinoma

The first case report was in 1952, which described a link between a hidradenoma and hidradenocarcinoma of the vulvae.1 This was followed by dermatological literature, which described a variant of hidradenocarcinoma known as clear cell type.2 Recent case reports throughout the literature have described this carcinoma to involve other locations such as the eyelid, scalp, finger, and perianal involvement. [...] to the much more common squamous cell or basal cell carcinomas of the skin, hidradenocarcinoma are known to have a much higher rate of both local recurrences (14 to 20%)3 as well as lymphatic metastasis (20 to 24%).3 In general, these tumors are treated with a combination of surgical excision with assessment of the local lymph node basin by sentinel lymph node biopsy followed by chemotherapeutic protocols mirroring those used for breast cancer.4 Follow-up is directed toward early identification of local recurrence as well as distant spread to the draining lymph node basins with re-excision recommended.