Antibiotic-Impregnated Beads for the Treatment of Aortic Graft Infection

Infection of a prosthetic graft after replacement of the ascending aorta is an uncommon but life-threatening complication of surgery. We report the use of antibiotic-impregnated calcium sulfate beads in a patient with ascending aortic graft infection to provide localized, high-dose therapy to the in...

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Veröffentlicht in:	The Annals of thoracic surgery 2012-03, Vol.93 (3), p.984-985
Hauptverfasser:	Healy, Aaron H., MD, Reid, Bruce B., MD, Allred, Bryce D., MD, Doty, John R., MD
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Anti-Bacterial Agents - administration & dosage Aorta - surgery Biological and medical sciences Blood Vessel Prosthesis - adverse effects Cardiology. Vascular system Cardiothoracic Surgery Drug Carriers Humans Male Medical sciences Microspheres Pneumology Prosthesis-Related Infections - drug therapy Staphylococcal Infections - drug therapy Surgery Tobramycin - administration & dosage Vancomycin - administration & dosage
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Beschreibung
Zusammenfassung:	Infection of a prosthetic graft after replacement of the ascending aorta is an uncommon but life-threatening complication of surgery. We report the use of antibiotic-impregnated calcium sulfate beads in a patient with ascending aortic graft infection to provide localized, high-dose therapy to the infected region. Perigraft placement of antibiotic beads provides an alternative method for the treatment of aortic graft infection.
ISSN:	0003-4975 1552-6259
DOI:	10.1016/j.athoracsur.2011.07.066